Comprehensive analysis of normal adjacent to tumor transcriptomes

Normal tissue adjacent to the tumour (NAT) is often used as a control in cancer studies. Here, the authors analyse across cancer types the transcriptomes of healthy, NAT, and tumour tissues, and find that NAT presents a unique state, potentially due to inflammatory response of the NAT to the tumour...

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Autores principales:	Dvir Aran, Roman Camarda, Justin Odegaard, Hyojung Paik, Boris Oskotsky, Gregor Krings, Andrei Goga, Marina Sirota, Atul J. Butte
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/92442fbf71dc46038ab5ef9c6bf555db
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spelling	oai:doaj.org-article:92442fbf71dc46038ab5ef9c6bf555db2021-12-02T14:40:23ZComprehensive analysis of normal adjacent to tumor transcriptomes10.1038/s41467-017-01027-z2041-1723https://doaj.org/article/92442fbf71dc46038ab5ef9c6bf555db2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01027-zhttps://doaj.org/toc/2041-1723Normal tissue adjacent to the tumour (NAT) is often used as a control in cancer studies. Here, the authors analyse across cancer types the transcriptomes of healthy, NAT, and tumour tissues, and find that NAT presents a unique state, potentially due to inflammatory response of the NAT to the tumour tissue.Dvir AranRoman CamardaJustin OdegaardHyojung PaikBoris OskotskyGregor KringsAndrei GogaMarina SirotaAtul J. ButteNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dvir Aran Roman Camarda Justin Odegaard Hyojung Paik Boris Oskotsky Gregor Krings Andrei Goga Marina Sirota Atul J. Butte Comprehensive analysis of normal adjacent to tumor transcriptomes
description	Normal tissue adjacent to the tumour (NAT) is often used as a control in cancer studies. Here, the authors analyse across cancer types the transcriptomes of healthy, NAT, and tumour tissues, and find that NAT presents a unique state, potentially due to inflammatory response of the NAT to the tumour tissue.
format	article
author	Dvir Aran Roman Camarda Justin Odegaard Hyojung Paik Boris Oskotsky Gregor Krings Andrei Goga Marina Sirota Atul J. Butte
author_facet	Dvir Aran Roman Camarda Justin Odegaard Hyojung Paik Boris Oskotsky Gregor Krings Andrei Goga Marina Sirota Atul J. Butte
author_sort	Dvir Aran
title	Comprehensive analysis of normal adjacent to tumor transcriptomes
title_short	Comprehensive analysis of normal adjacent to tumor transcriptomes
title_full	Comprehensive analysis of normal adjacent to tumor transcriptomes
title_fullStr	Comprehensive analysis of normal adjacent to tumor transcriptomes
title_full_unstemmed	Comprehensive analysis of normal adjacent to tumor transcriptomes
title_sort	comprehensive analysis of normal adjacent to tumor transcriptomes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/92442fbf71dc46038ab5ef9c6bf555db
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Comprehensive analysis of normal adjacent to tumor transcriptomes

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