Scaffold-based pan-agonist design for the PPARα, PPARβ and PPARγ receptors.

As important members of nuclear receptor superfamily, Peroxisome proliferator-activated receptors (PPAR) play essential roles in regulating cellular differentiation, development, metabolism, and tumorigenesis of higher organisms. The PPAR receptors have 3 identified subtypes: PPARα, PPARβ and PPARγ,...

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Autores principales: Li-Song Zhang, Shu-Qing Wang, Wei-Ren Xu, Run-Ling Wang, Jing-Fang Wang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/9250f83d504e40b6929ec9013fde4d17
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