Scaffold-based pan-agonist design for the PPARα, PPARβ and PPARγ receptors.
As important members of nuclear receptor superfamily, Peroxisome proliferator-activated receptors (PPAR) play essential roles in regulating cellular differentiation, development, metabolism, and tumorigenesis of higher organisms. The PPAR receptors have 3 identified subtypes: PPARα, PPARβ and PPARγ,...
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Main Authors: | , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Subjects: | |
Online Access: | https://doaj.org/article/9250f83d504e40b6929ec9013fde4d17 |
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