Designing an irreversible metabolic switch for scalable induction of microbial chemical production

A promising strategy to increase product synthesis from bacteria uses inducible systems to switch metabolism to production. Here, the authors use models to show how engineering positive feedback loops into the genetic circuitry creates a switch that requires only temporary induction with a cheap nut...

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Autores principales: Ahmad A. Mannan, Declan G. Bates
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/925f3bab049a46a39d8569145e04adbe
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