Permeation through the cell membrane of a boron-based β-lactamase inhibitor.

Bacteria express beta-lactamases to counteract the beneficial action of antibiotics. Benzo[b]-thiophene-2-boronic acid (BZB) derivatives are β-lactamase inhibitors and, as such, promising compounds to be associated with β-lactam antibacterial therapies. The uncharged form of BZB, in particular, is s...

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Autores principales: Manuela Minozzi, Gianluca Lattanzi, Roland Benz, Maria P Costi, Alberto Venturelli, Paolo Carloni
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/92660a032c3f4a1581d416a3b117cc21
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