The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation

Abstract Increased airway smooth muscle (ASM) mass is a prominent hallmark of airway remodeling in asthma. Inhaled corticosteroids and long-acting beta2-agonists remain the mainstay of asthma therapy, however are not curative and ineffective in attenuating airway remodeling. The geranyl acetophenone...

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Auteurs principaux: Hui Min Yap, Yu Zhao Lee, Hanis Hazeera Harith, Chau Ling Tham, Manraj Singh Cheema, Khozirah Shaari, Daud Ahmad Israf
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/928b5b5919c84c4aa574d2dabe069998
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