Simultaneous targeting of mitochondria and monocytes enhances neuroprotection against ischemia–reperfusion injury
Abstract Ischemia–reperfusion injury impairs the efficacy of reperfusion therapy after ischemic stroke. Cyclophilin D (CypD)-mediated openings of mitochondrial permeability transition pore (mPTP) and subsequent monocyte-mediated inflammation are considered as major mechanisms of reperfusion injury....
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Auteurs principaux: | , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/929409dd3f8a48648a7dd82691a4b1ce |
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