CNS GNPDA2 Does Not Control Appetite, but Regulates Glucose Homeostasis

GNPDA2 has been associated with human obesity and type-2 diabetes by using a GWAS approach. GNPDA2 is an enzyme involved in the hexosamine biosynthesis pathway, which is known to be important for nutrient sensing in various organism. Its counter enzyme, GFAT, has previously been shown to be importan...

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Auteurs principaux: Ruth Gutierrez-Aguilar, Bernadette E. Grayson, Dong-Hoon Kim, Suma Yalamanchili, Mario L. Calcagno, Stephen C. Woods, Randy J. Seeley
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/929cf6355a8040a892243288d86fea76
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