CNS GNPDA2 Does Not Control Appetite, but Regulates Glucose Homeostasis

GNPDA2 has been associated with human obesity and type-2 diabetes by using a GWAS approach. GNPDA2 is an enzyme involved in the hexosamine biosynthesis pathway, which is known to be important for nutrient sensing in various organism. Its counter enzyme, GFAT, has previously been shown to be importan...

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Bibliographic Details
Main Authors: Ruth Gutierrez-Aguilar, Bernadette E. Grayson, Dong-Hoon Kim, Suma Yalamanchili, Mario L. Calcagno, Stephen C. Woods, Randy J. Seeley
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/929cf6355a8040a892243288d86fea76
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