Disrupted metabolic connectivity in dopaminergic and cholinergic networks at different stages of dementia from 18F-FDG PET brain persistent homology network

Abstract Dementia is related to the cellular accumulation of β-amyloid plaques, tau aggregates, or α-synuclein aggregates, or to neurotransmitter deficiencies in the dopaminergic and cholinergic pathways. Cellular and neurochemical changes are both involved in dementia pathology. However, the role o...

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Bibliographic Details
Main Authors: Tun-Wei Hsu, Jong-Ling Fuh, Da-Wei Wang, Li-Fen Chen, Chia-Jung Chang, Wen-Sheng Huang, Hsiu-Mei Wu, Wan-Yuo Guo
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Q
Online Access:https://doaj.org/article/92a1a544d3d8466c8e8172363f08a084
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