Aciculatin inhibits granulocyte colony-stimulating factor production by human interleukin 1β-stimulated fibroblast-like synoviocytes.

The expression of granulocyte colony-stimulating factor (G-CSF), the major regulator of neutrophil maturation, by human fibroblast-like synoviocytes (FLS) can be stimulated by the inflammatory cytokine interleukin-1β (IL-1β). G-CSF is known to contribute to the pathologic processes of destructive ar...

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Autores principales: Kao-Shang Shih, Jyh-Horng Wang, Yi-Wen Wu, Che-Ming Teng, Chien-Chih Chen, Chia-Ron Yang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/92a273ec9c594c3aaf7c21763ad27388
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