Protein C inhibitor--a novel antimicrobial agent.

Protein C inhibitor (PCI) is a heparin-binding serine proteinase inhibitor belonging to the family of serpin proteins. Here we describe that PCI exerts broad antimicrobial activity against bacterial pathogens. This ability is mediated by the interaction of PCI with lipid membranes, which subsequentl...

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Autores principales: Erik Malmström, Matthias Mörgelin, Martin Malmsten, Linda Johansson, Anna Norrby-Teglund, Oonagh Shannon, Artur Schmidtchen, Joost C M Meijers, Heiko Herwald
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/92aabe1548634f01850a5eaa25f6ec90
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