TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival
Interleukin-15 (IL-15) regulates the homeostasis of many immune cell types, including natural killer T (NKT) cells, but the underlying mechanism is not completely clear. Here the authors analyse Tbkbp1-deficient mice and show that IL-15 induces Tbkbp1-dependent autophagy to modulate NKT survival.
Enregistré dans:
Auteurs principaux: | , , , , , , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/92aecf591e844ff9a8cf1378b35aec46 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|