Clinical Clostridium difficile: clonality and pathogenicity locus diversity.
Clostridium difficile infection (CDI) is an important cause of mortality and morbidity in healthcare settings. The major virulence determinants are large clostridial toxins, toxin A (tcdA) and toxin B (tcdB), encoded within the pathogenicity locus (PaLoc). Isolates vary in pathogenicity from hypervi...
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Main Authors: | Kate E Dingle, David Griffiths, Xavier Didelot, Jessica Evans, Alison Vaughan, Melina Kachrimanidou, Nicole Stoesser, Keith A Jolley, Tanya Golubchik, Rosalind M Harding, Tim E Peto, Warren Fawley, A Sarah Walker, Mark Wilcox, Derrick W Crook |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/92cb5d60d0a1471a9ee089980e7b83ff |
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