Phytomedicine in Disease Management: In-Silico Analysis of the Binding Affinity of Artesunate and Azadirachtin for Malaria Treatment

In the rural communities of sub-Saharan African (sSA) countries, malaria is being managed using phytocompounds. Artesunate is reported to inhibit Gephyrin E, a central, multi-domain scaffolding protein of inhibitory post-synapses. Neem plant and its metabolites like azadirachtin are being indicated...

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Main Authors: Michael P. Okoh, Rajeev K. Singla, Chijioke Madu, Opeyemi Soremekun, Johnson Adejoh, Lukman A. Alli, Bairong Shen
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/92d69604b2a64890b2d86338d642615a
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