Zebrafish preserve global germline DNA methylation while sex-linked rDNA is amplified and demethylated during feminisation

Germline cells transfer genetic information to offspring, and in zebrafish, drive sex determination. Here the authors report that, unlike mammals, the germline of zebrafish does not undergo genome-wide DNA methylation erasure, while amplifying and demethylating sex-linked rDNA during feminisation.

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Detalles Bibliográficos
Autores principales: Oscar Ortega-Recalde, Robert C. Day, Neil J. Gemmell, Timothy A. Hore
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/930144fede1144be9a981b3a57912b2a
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