TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway

Abstract Transmembrane protein (TMEM) is a family of protein that spans cytoplasmic membranes and allows cell–cell and cell–environment communication. Dysregulation of TMEMs has been observed in multiple cancers. However, little is known about TMEM116 in cancer development. In this study, we demonst...

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Autores principales: Suhong Zhang, Haiting Dai, Wenya Li, Runming Wang, Hanyu Wu, Ming Shen, Ye Hu, Lixin Xie, Yiming Xing
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/932f2a4982f340baad1ead0b9e90513c
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