TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway

Abstract Transmembrane protein (TMEM) is a family of protein that spans cytoplasmic membranes and allows cell–cell and cell–environment communication. Dysregulation of TMEMs has been observed in multiple cancers. However, little is known about TMEM116 in cancer development. In this study, we demonst...

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Bibliographic Details
Main Authors: Suhong Zhang, Haiting Dai, Wenya Li, Runming Wang, Hanyu Wu, Ming Shen, Ye Hu, Lixin Xie, Yiming Xing
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/932f2a4982f340baad1ead0b9e90513c
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