A simple method of hiPSCs differentiation into insulin-producing cells is improved with vitamin C and RepSox.

Human induced pluripotent stem cells (hiPSCs) are considered a promising source of pancreatic β-cells for the treatment of diabetes. However, this approach is limited by issues such as low efficiency and high cost. Here, we have developed a new protocol to induce insulin-producing cells. To reduce c...

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Autores principales: Ayumi Horikawa, Keiko Mizuno, Kyoko Tsuda, Takayoshi Yamamoto, Tatsuo Michiue
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/938938cb370142d4a928cbde5fdd4754
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