Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons

Astrocyte in the brain regulates synaptic transmission by releasing gliotransmitters. Here, Tan and colleagues use optogenetic stimulation of astrocytes to show differential neuronal subtype-specific purinoceptor responses to astrocytic ATP release to affect network excitability.

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Autores principales: Zhibing Tan, Yu Liu, Wang Xi, Hui-fang Lou, Liya Zhu, Zhifei Guo, Lin Mei, Shumin Duan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/938970f39c4243aea675e30a2ba9ce40
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