Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons
Astrocyte in the brain regulates synaptic transmission by releasing gliotransmitters. Here, Tan and colleagues use optogenetic stimulation of astrocytes to show differential neuronal subtype-specific purinoceptor responses to astrocytic ATP release to affect network excitability.
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Nature Portfolio
2017
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oai:doaj.org-article:938970f39c4243aea675e30a2ba9ce402021-12-02T17:06:04ZGlia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons10.1038/ncomms137722041-1723https://doaj.org/article/938970f39c4243aea675e30a2ba9ce402017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13772https://doaj.org/toc/2041-1723Astrocyte in the brain regulates synaptic transmission by releasing gliotransmitters. Here, Tan and colleagues use optogenetic stimulation of astrocytes to show differential neuronal subtype-specific purinoceptor responses to astrocytic ATP release to affect network excitability.Zhibing TanYu LiuWang XiHui-fang LouLiya ZhuZhifei GuoLin MeiShumin DuanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q Zhibing Tan Yu Liu Wang Xi Hui-fang Lou Liya Zhu Zhifei Guo Lin Mei Shumin Duan Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons |
description |
Astrocyte in the brain regulates synaptic transmission by releasing gliotransmitters. Here, Tan and colleagues use optogenetic stimulation of astrocytes to show differential neuronal subtype-specific purinoceptor responses to astrocytic ATP release to affect network excitability. |
format |
article |
author |
Zhibing Tan Yu Liu Wang Xi Hui-fang Lou Liya Zhu Zhifei Guo Lin Mei Shumin Duan |
author_facet |
Zhibing Tan Yu Liu Wang Xi Hui-fang Lou Liya Zhu Zhifei Guo Lin Mei Shumin Duan |
author_sort |
Zhibing Tan |
title |
Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons |
title_short |
Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons |
title_full |
Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons |
title_fullStr |
Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons |
title_full_unstemmed |
Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons |
title_sort |
glia-derived atp inversely regulates excitability of pyramidal and cck-positive neurons |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/938970f39c4243aea675e30a2ba9ce40 |
work_keys_str_mv |
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_version_ |
1718381742849523712 |