CD73-positive extracellular vesicles promote glioblastoma immunosuppression by inhibiting T-cell clonal expansion

Abstract Extracellular vesicles are involved in the occurrence, progression and metastasis of glioblastoma (GBM). GBM can secrete a variety of tumour-derived extracellular vesicles (TDEVs) with high immunosuppressive activity that remotely suppress the systemic immune system, and therapy targeting T...

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Bibliographic Details
Main Authors: Ming Wang, Jiaoying Jia, Yan Cui, Yong Peng, Yugang Jiang
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/938cd1214546425da9692985f0ad213e
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