Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis
The visualisation of the bone metastasis process in a spatial temporal manner is lacking. Here, the authors use three-dimensional quantitative imaging and show that mouse mammary tumour cells preferentially home to endothelial subtype type H vessels within the bone marrow and remodel this vasculatur...
Guardado en:
Autores principales: | Raymond K. H. Yip, Joel S. Rimes, Bianca D. Capaldo, François Vaillant, Kellie A. Mouchemore, Bhupinder Pal, Yunshun Chen, Elliot Surgenor, Andrew J. Murphy, Robin L. Anderson, Gordon K. Smyth, Geoffrey J. Lindeman, Edwin D. Hawkins, Jane E. Visvader |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/938d0b41436b4974bba32259f0e9856a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling
por: Bhupinder Pal, et al.
Publicado: (2017) -
Essential role for a novel population of binucleated mammary epithelial cells in lactation
por: Anne C. Rios, et al.
Publicado: (2016) -
Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers
por: Rachel M. Koldej, et al.
Publicado: (2021) -
Bone Marrow Adipocytes: A Critical Player in the Bone Marrow Microenvironment
por: Lipeng Wang, et al.
Publicado: (2021) -
Mammary epithelial morphogenesis in 3D combinatorial microenvironments
por: Raphaelle Luisier, et al.
Publicado: (2020)