Single-cell RNA transcriptome landscape of hepatocytes and non-parenchymal cells in healthy and NAFLD mouse liver

par Qi Su, Sun Y. Kim, Funmi Adewale, Ye Zhou, Christina Aldler, Min Ni, Yi Wei, Michael E. Burczynski, Gurinder S. Atwal, Mark W. Sleeman, Andrew J. Murphy, Yurong Xin, Xiping Cheng
Publié 2021

Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis

par Raymond K. H. Yip, Joel S. Rimes, Bianca D. Capaldo, François Vaillant, Kellie A. Mouchemore, Bhupinder Pal, Yunshun Chen, Elliot Surgenor, Andrew J. Murphy, Robin L. Anderson, Gordon K. Smyth, Geoffrey J. Lindeman, Edwin D. Hawkins, Jane E. Visvader
Publié 2021

Activin A more prominently regulates muscle mass in primates than does GDF8

par Esther Latres, Jason Mastaitis, Wen Fury, Lawrence Miloscio, Jesus Trejos, Jeffrey Pangilinan, Haruka Okamoto, Katie Cavino, Erqian Na, Angelos Papatheodorou, Tobias Willer, Yu Bai, Jee Hae Kim, Ashique Rafique, Stephen Jaspers, Trevor Stitt, Andrew J. Murphy, George D. Yancopoulos, Jesper Gromada
Publié 2017

Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes

par Casandra Panea, Ruoyu Zhang, Jeffrey VanValkenburgh, Min Ni, Christina Adler, Yi Wei, Francisca Ochoa, Jennifer Schmahl, Yajun Tang, Chia-Jen Siao, William Poueymirou, Jennifer Espert, Wei Keat Lim, Gurinder S. Atwal, Andrew J. Murphy, Matthew A. Sleeman, Zaruhi Hovhannisyan, Sokol Haxhinasto
Publié 2021

An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence

par Chang-Han Lee, Tae Hyun Kang, Ophélie Godon, Makiko Watanabe, George Delidakis, Caitlin M. Gillis, Delphine Sterlin, David Hardy, Michel Cogné, Lynn E. Macdonald, Andrew J. Murphy, Naxin Tu, Jiwon Lee, Jonathan R. McDaniel, Emily Makowski, Peter M. Tessier, Aaron S. Meyer, Pierre Bruhns, George Georgiou
Publié 2019

Publisher Correction: An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence

par Chang-Han Lee, Tae Hyun Kang, Ophélie Godon, Makiko Watanabe, George Delidakis, Caitlin M. Gillis, Delphine Sterlin, David Hardy, Michel Cogné, Lynn E. Macdonald, Andrew J. Murphy, Naxin Tu, Jiwon Lee, Jonathan R. McDaniel, Emily Makowski, Peter M. Tessier, Aaron S. Meyer, Pierre Bruhns, George Georgiou
Publié 2019

High intraluminal pressure promotes vascular inflammation via caveolin-1

par Danielle L. Michell, Waled A. Shihata, Karen L. Andrews, Nurul Aisha Zainal Abidin, Ann-Maree Jefferis, Amanda K. Sampson, Natalie G. Lumsden, Olivier Huet, Marie-Odile Parat, Garry L. Jennings, Robert G. Parton, Kevin J. Woollard, David M. Kaye, Jaye P. F. Chin-Dusting, Andrew J. Murphy
Publié 2021

Author Correction: Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo

par Cheng Xue Qin, Siobhan B. Finlayson, Annas Al-Sharea, Mitchel Tate, Miles J. De Blasio, Minh Deo, Sarah Rosli, Darnel Prakoso, Colleen J. Thomas, Helen Kiriazis, Eleanor Gould, Yuan H. Yang, Eric F. Morand, Mauro Perretti, Andrew J. Murphy, Xiao-Jun Du, Xiao-Ming Gao, Rebecca H. Ritchie
Publié 2018

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

par Andrew J. Murphy, Xiang Chen, Emilia M. Pinto, Justin S. Williams, Michael R. Clay, Stanley B. Pounds, Xueyuan Cao, Lei Shi, Tong Lin, Geoffrey Neale, Christopher L. Morton, Mary A. Woolard, Heather L. Mulder, Hyea Jin Gil, Jerold E. Rehg, Catherine A. Billups, Matthew L. Harlow, Jeffrey S. Dome, Peter J. Houghton, John Easton, Jinghui Zhang, Rani E. George, Gerard P. Zambetti, Andrew M. Davidoff
Publié 2019

A novel bispecific antibody platform to direct complement activity for efficient lysis of target cells

par Jonathan W. Cruz, Ermelinda Damko, Bhavika Modi, Naxin Tu, Karoline Meagher, Vera Voronina, Hans Gartner, George Ehrlich, Ashique Rafique, Robert Babb, Priya Aneja, Terra B. Potocky, Amanda D’ Orvilliers, Alida Coppi, Sook Yen E, Haibo Qiu, Courtney M. Williams, Brandy L. Bennett, Gang Chen, Lynn Macdonald, William Olson, John C. Lin, Neil Stahl, Andrew J. Murphy, Christos A. Kyratsous, Brinda C. Prasad
Publié 2019

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

par Viktoria Gusarova, Colm O’Dushlaine, Tanya M. Teslovich, Peter N. Benotti, Tooraj Mirshahi, Omri Gottesman, Cristopher V. Van Hout, Michael F. Murray, Anubha Mahajan, Jonas B. Nielsen, Lars Fritsche, Anders Berg Wulff, Daniel F. Gudbjartsson, Marketa Sjögren, Connor A. Emdin, Robert A. Scott, Wen-Jane Lee, Aeron Small, Lydia C. Kwee, Om Prakash Dwivedi, Rashmi B. Prasad, Shannon Bruse, Alexander E. Lopez, John Penn, Anthony Marcketta, Joseph B. Leader, Christopher D. Still, H. Lester Kirchner, Uyenlinh L. Mirshahi, Amr H. Wardeh, Cassandra M. Hartle, Lukas Habegger, Samantha N. Fetterolf, Teresa Tusie-Luna, Andrew P. Morris, Hilma Holm, Valgerdur Steinthorsdottir, Patrick Sulem, Unnur Thorsteinsdottir, Jerome I. Rotter, Lee-Ming Chuang, Scott Damrauer, David Birtwell, Chad M. Brummett, Amit V. Khera, Pradeep Natarajan, Marju Orho-Melander, Jason Flannick, Luca A. Lotta, Cristen J. Willer, Oddgeir L. Holmen, Marylyn D. Ritchie, David H. Ledbetter, Andrew J. Murphy, Ingrid B. Borecki, Jeffrey G. Reid, John D. Overton, Ola Hansson, Leif Groop, Svati H. Shah, William E. Kraus, Daniel J. Rader, Yii-Der I. Chen, Kristian Hveem, Nicholas J. Wareham, Sekar Kathiresan, Olle Melander, Kari Stefansson, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Goncalo R. Abecasis, David Altshuler, Jose C. Florez, Michael Boehnke, Mark I. McCarthy, George D. Yancopoulos, David J. Carey, Alan R. Shuldiner, Aris Baras, Frederick E. Dewey, Jesper Gromada
Publié 2018