CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

por Malgorzata Krajewska, Ruben Dries, Andrew V. Grassetti, Sofia Dust, Yang Gao, Hao Huang, Bandana Sharma, Daniel S. Day, Nicholas Kwiatkowski, Monica Pomaville, Oliver Dodd, Edmond Chipumuro, Tinghu Zhang, Arno L. Greenleaf, Guo-Cheng Yuan, Nathanael S. Gray, Richard A. Young, Matthias Geyer, Scott A. Gerber, Rani E. George
Publicado 2019

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

por Andrew J. Murphy, Xiang Chen, Emilia M. Pinto, Justin S. Williams, Michael R. Clay, Stanley B. Pounds, Xueyuan Cao, Lei Shi, Tong Lin, Geoffrey Neale, Christopher L. Morton, Mary A. Woolard, Heather L. Mulder, Hyea Jin Gil, Jerold E. Rehg, Catherine A. Billups, Matthew L. Harlow, Jeffrey S. Dome, Peter J. Houghton, John Easton, Jinghui Zhang, Rani E. George, Gerard P. Zambetti, Andrew M. Davidoff
Publicado 2019

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

por Matthew Wong, Yuting Sun, Zhichao Xi, Giorgio Milazzo, Rebecca C. Poulos, Christoph Bartenhagen, Jessica L. Bell, Chelsea Mayoh, Nicholas Ho, Andrew E. Tee, Xiaoqiong Chen, Yang Li, Roberto Ciaccio, Pei Y. Liu, Chen C. Jiang, Qing Lan, Nisitha Jayatilleke, Belamy B. Cheung, Michelle Haber, Murray D. Norris, Xu D. Zhang, Glenn M. Marshall, Jenny Y. Wang, Stefan Hüttelmaier, Matthias Fischer, Jason W. H. Wong, Hongxi Xu, Giovanni Perini, Qihan Dong, Rani E. George, Tao Liu
Publicado 2019

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

por Maged Zeineldin, Sara Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, Rosa Nguyen, Jackie Norrie, John Easton, Heather Mulder, Donald Yergeau, Yanling Liu, Jianrong Wu, Collin Van Ryn, Arlene Naranjo, Michael D. Hogarty, Marcin M. Kamiński, Marc Valentine, Shondra M. Pruett-Miller, Alberto Pappo, Jinghui Zhang, Michael R. Clay, Armita Bahrami, Peter Vogel, Seungjae Lee, Anang Shelat, Jay F. Sarthy, Michael P. Meers, Rani E. George, Elaine R. Mardis, Richard K. Wilson, Steven Henikoff, James R. Downing, Michael A. Dyer
Publicado 2020