RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors

RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors

Mature piRNAs are produced from long single-stranded precursor RNAs. Here the authors show that RNase κ generates 2′,3′-cyclic phosphate-containing piRNA precursors and promotes piRNA production.

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Autores principales: Megumi Shigematsu, Takuya Kawamura, Keisuke Morichika, Natsuko Izumi, Takashi Kiuchi, Shozo Honda, Venetia Pliatsika, Ryuma Matsubara, Isidore Rigoutsos, Susumu Katsuma, Yukihide Tomari, Yohei Kirino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/939dadb0138143918c8127b14eb6589f
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https://doaj.org/article/939dadb0138143918c8127b14eb6589f

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