RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors

Mature piRNAs are produced from long single-stranded precursor RNAs. Here the authors show that RNase κ generates 2′,3′-cyclic phosphate-containing piRNA precursors and promotes piRNA production.

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Autores principales:	Megumi Shigematsu, Takuya Kawamura, Keisuke Morichika, Natsuko Izumi, Takashi Kiuchi, Shozo Honda, Venetia Pliatsika, Ryuma Matsubara, Isidore Rigoutsos, Susumu Katsuma, Yukihide Tomari, Yohei Kirino
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/939dadb0138143918c8127b14eb6589f
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spelling	oai:doaj.org-article:939dadb0138143918c8127b14eb6589f2021-12-02T16:26:26ZRNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors10.1038/s41467-021-24681-w2041-1723https://doaj.org/article/939dadb0138143918c8127b14eb6589f2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24681-whttps://doaj.org/toc/2041-1723Mature piRNAs are produced from long single-stranded precursor RNAs. Here the authors show that RNase κ generates 2′,3′-cyclic phosphate-containing piRNA precursors and promotes piRNA production.Megumi ShigematsuTakuya KawamuraKeisuke MorichikaNatsuko IzumiTakashi KiuchiShozo HondaVenetia PliatsikaRyuma MatsubaraIsidore RigoutsosSusumu KatsumaYukihide TomariYohei KirinoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Megumi Shigematsu Takuya Kawamura Keisuke Morichika Natsuko Izumi Takashi Kiuchi Shozo Honda Venetia Pliatsika Ryuma Matsubara Isidore Rigoutsos Susumu Katsuma Yukihide Tomari Yohei Kirino RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
description	Mature piRNAs are produced from long single-stranded precursor RNAs. Here the authors show that RNase κ generates 2′,3′-cyclic phosphate-containing piRNA precursors and promotes piRNA production.
format	article
author	Megumi Shigematsu Takuya Kawamura Keisuke Morichika Natsuko Izumi Takashi Kiuchi Shozo Honda Venetia Pliatsika Ryuma Matsubara Isidore Rigoutsos Susumu Katsuma Yukihide Tomari Yohei Kirino
author_facet	Megumi Shigematsu Takuya Kawamura Keisuke Morichika Natsuko Izumi Takashi Kiuchi Shozo Honda Venetia Pliatsika Ryuma Matsubara Isidore Rigoutsos Susumu Katsuma Yukihide Tomari Yohei Kirino
author_sort	Megumi Shigematsu
title	RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
title_short	RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
title_full	RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
title_fullStr	RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
title_full_unstemmed	RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors
title_sort	rnase κ promotes robust pirna production by generating 2′,3′-cyclic phosphate-containing precursors
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/939dadb0138143918c8127b14eb6589f
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RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors

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