Genetic characterization of the Drosophila birt-hogg-dubé syndrome gene.

Folliculin (FLCN) is a conserved tumor suppressor gene whose loss is associated with the human Birt-Hogg-Dubé (BHD) syndrome. However, its molecular functions remain largely unknown. In this work, we generated a Drosophila BHD model through genomic deletion of the FLCN gene (DBHD(-) ). The DBHD muta...

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Autores principales: Wei Liu, Zhi Chen, Yansen Ma, Xiaochun Wu, Yaping Jin, Steven Hou
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/93b77164b22b496cb31112d1b22b8d02
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