Our Exciting Journey to ACT-451840
We describe our work resulting in the selection of ACT-451840 ( 38 ) as a novel antimalarial drug with a novel mode of action. The compound was broadly characterized in vitro as well as in vivo in rat PK experiments as well as two different mouse malaria models. In the P. berghei infected mouse mode...
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | DE EN FR |
| Publié: |
Swiss Chemical Society
2021
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| Accès en ligne: | https://doaj.org/article/93b7c702dfa74ab3aef04287a807090c |
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