Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

The assembly and maturation of the early life microbiome has life-long effects on human health. Here, the authors combine omics, functional assays and structural analyses to characterize the catabolic pathways that support the growth of butyrate producing Clostridiales members from the Roseburia and...

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Autores principales:	Michael Jakob Pichler, Chihaya Yamada, Bashar Shuoker, Camila Alvarez-Silva, Aina Gotoh, Maria Louise Leth, Erwin Schoof, Toshihiko Katoh, Mikiyasu Sakanaka, Takane Katayama, Chunsheng Jin, Niclas G. Karlsson, Manimozhiyan Arumugam, Shinya Fushinobu, Maher Abou Hachem
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/93e13acc192c463a8e81c96141510b43
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spelling	oai:doaj.org-article:93e13acc192c463a8e81c96141510b432021-12-02T18:18:46ZButyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways10.1038/s41467-020-17075-x2041-1723https://doaj.org/article/93e13acc192c463a8e81c96141510b432020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17075-xhttps://doaj.org/toc/2041-1723The assembly and maturation of the early life microbiome has life-long effects on human health. Here, the authors combine omics, functional assays and structural analyses to characterize the catabolic pathways that support the growth of butyrate producing Clostridiales members from the Roseburia and Eubacterium, on distinct human milk oligosaccharides.Michael Jakob PichlerChihaya YamadaBashar ShuokerCamila Alvarez-SilvaAina GotohMaria Louise LethErwin SchoofToshihiko KatohMikiyasu SakanakaTakane KatayamaChunsheng JinNiclas G. KarlssonManimozhiyan ArumugamShinya FushinobuMaher Abou HachemNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael Jakob Pichler Chihaya Yamada Bashar Shuoker Camila Alvarez-Silva Aina Gotoh Maria Louise Leth Erwin Schoof Toshihiko Katoh Mikiyasu Sakanaka Takane Katayama Chunsheng Jin Niclas G. Karlsson Manimozhiyan Arumugam Shinya Fushinobu Maher Abou Hachem Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
description	The assembly and maturation of the early life microbiome has life-long effects on human health. Here, the authors combine omics, functional assays and structural analyses to characterize the catabolic pathways that support the growth of butyrate producing Clostridiales members from the Roseburia and Eubacterium, on distinct human milk oligosaccharides.
format	article
author	Michael Jakob Pichler Chihaya Yamada Bashar Shuoker Camila Alvarez-Silva Aina Gotoh Maria Louise Leth Erwin Schoof Toshihiko Katoh Mikiyasu Sakanaka Takane Katayama Chunsheng Jin Niclas G. Karlsson Manimozhiyan Arumugam Shinya Fushinobu Maher Abou Hachem
author_facet	Michael Jakob Pichler Chihaya Yamada Bashar Shuoker Camila Alvarez-Silva Aina Gotoh Maria Louise Leth Erwin Schoof Toshihiko Katoh Mikiyasu Sakanaka Takane Katayama Chunsheng Jin Niclas G. Karlsson Manimozhiyan Arumugam Shinya Fushinobu Maher Abou Hachem
author_sort	Michael Jakob Pichler
title	Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
title_short	Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
title_full	Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
title_fullStr	Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
title_full_unstemmed	Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
title_sort	butyrate producing colonic clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/93e13acc192c463a8e81c96141510b43
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Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

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