Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma

In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laborato...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Daorina Bao, Ying Tan, Xiaojuan Yu, Bingjie Wang, Hui Wang, Rong Xu, Fude Zhou, Minghui Zhao
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://doaj.org/article/93e176f6bf9e4262897baf1cc4ef8173
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
Description
Résumé:In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laboratory criteria, which showed impaired renal function and nephrotic syndrome with predominant hematuria. Renal biopsy showed IV+V lupus nephritis with highly infiltrated lymphoid cells in the kidney. Secondary lupus nephritis was suspected based on the possible pathogenesis of glomerular injury due to mantle cell lymphoma. Low-dose dexamethasone, rituximab, and lenalidomide were immediately started on the patient, and his renal function was improved after the first cycle of chemotherapy.