Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
Sterol lipids are crucial for maintaining proper brain function. Here, the authors combine ion mobility-mass spectrometry and machine learning to assemble a sterol lipid library and characterize differences in sterol lipids across ten brain regions and two age groups in mice.
Saved in:
Main Authors: | Tongzhou Li, Yandong Yin, Zhiwei Zhou, Jiaqian Qiu, Wenbin Liu, Xueting Zhang, Kaiwen He, Yuping Cai, Zheng-Jiang Zhu |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/93e2745d67af43f4871d194c83d08ba0 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Sterols are required for the coordinated assembly of lipid droplets in developing seeds
by: Linhui Yu, et al.
Published: (2021) -
Ion mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics
by: Zhiwei Zhou, et al.
Published: (2020) -
Ion mobility conformational lipid atlas for high confidence lipidomics
by: Katrina L. Leaptrot, et al.
Published: (2019) -
Partial Correlation between Spatial and Temporal Regularities of Human Mobility
by: Wei Geng, et al.
Published: (2017) -
Thermodynamics of lipid multi-lamellar vesicles in presence of sterols at high hydrostatic pressure
by: J. Peters, et al.
Published: (2017)