Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1.

Mitochondrial shape is determined by fission and fusion reactions catalyzed by large GTPases of the dynamin family, mutation of which can cause neurological dysfunction. While fission-inducing protein phosphatases have been identified, the identity of opposing kinase signaling complexes has remained...

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Autores principales: Ronald A Merrill, Ruben K Dagda, Audrey S Dickey, J Thomas Cribbs, Steven H Green, Yuriy M Usachev, Stefan Strack
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/9416d933b26d4774ad931fda500fafb0
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