Phagocytic and pinocytic uptake of cholesterol in Tetrahymena thermophila impact differently on gene regulation for sterol homeostasis

Abstract The ciliate Tetrahymena thermophila can either synthesize tetrahymanol or when available, assimilate and modify sterols from its diet. This metabolic shift is mainly driven by transcriptional regulation of genes for tetrahymanol synthesis (TS) and sterol bioconversion (SB). The mechanistic...

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Auteurs principaux: Josefina Hernández, Matías Gabrielli, Joaquín Costa, Antonio D. Uttaro
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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R
Q
Accès en ligne:https://doaj.org/article/9428f774488a4c9aabdfd53576781405
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