Model Balancing: A Search for In-Vivo Kinetic Constants and Consistent Metabolic States

Enzyme kinetic constants in vivo are largely unknown, which limits the construction of large metabolic models. Given measured metabolic fluxes, metabolite concentrations, and enzyme concentrations, these constants may be inferred by model fitting, but the estimation problems are hard to solve if mod...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Wolfram Liebermeister, Elad Noor
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Acceso en línea:https://doaj.org/article/9430ea81edfd400eb5fb37d31353089d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!