Tau deposition is associated with functional isolation of the hippocampus in aging

Deposition of tau protein aggregates occurs during aging and Alzheimer disease. Here, the authors show that tau burden in the anterior-temporal memory network is associated with disrupted fMRI connectivity and functional isolation of the hippocampus from other memory network components.

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Auteurs principaux: Theresa M. Harrison, Anne Maass, Jenna N. Adams, Richard Du, Suzanne L. Baker, William J. Jagust
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/943d6b83e00c49b4bc60134224b62d84
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