Tau deposition is associated with functional isolation of the hippocampus in aging

Deposition of tau protein aggregates occurs during aging and Alzheimer disease. Here, the authors show that tau burden in the anterior-temporal memory network is associated with disrupted fMRI connectivity and functional isolation of the hippocampus from other memory network components.

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Bibliographic Details
Main Authors: Theresa M. Harrison, Anne Maass, Jenna N. Adams, Richard Du, Suzanne L. Baker, William J. Jagust
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/943d6b83e00c49b4bc60134224b62d84
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