Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP–PKA signaling

The molecular mechanism by which clock neurons transmit timing information to non-clock neurons is poorly understood. Here, the authors show that circadian clocks drive rhythmic expression of hundreds of genes in mushroom body neurons and drive calcium rhythms via NF1-cAMP/PKAC1 signalling in Drosop...

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Bibliographic Details
Main Authors: Pedro Machado Almeida, Blanca Lago Solis, Luca Stickley, Alexis Feidler, Emi Nagoshi
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/94595f06ca7140c8bcb73b922389b343
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