Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP–PKA signaling
The molecular mechanism by which clock neurons transmit timing information to non-clock neurons is poorly understood. Here, the authors show that circadian clocks drive rhythmic expression of hundreds of genes in mushroom body neurons and drive calcium rhythms via NF1-cAMP/PKAC1 signalling in Drosop...
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Autores principales: | Pedro Machado Almeida, Blanca Lago Solis, Luca Stickley, Alexis Feidler, Emi Nagoshi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/94595f06ca7140c8bcb73b922389b343 |
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