The genomic landscape of TP53 and p53 annotated high grade ovarian serous carcinomas from a defined founder population associated with patient outcome.

The genomic landscape of TP53 and p53 annotated high grade ovarian serous carcinomas from a defined founder population associated with patient outcome.

High-grade ovarian serous carcinomas (HGSC) are characterized by TP53 mutations and non-random patterns of chromosomal anomalies, where the nature of the TP53 mutation may correlate with clinical outcome. However, the frequency of common somatic genomic events occurring in HGSCs from demographically...

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Main Authors: Paulina M Wojnarowicz, Kathleen Klein Oros, Michael C J Quinn, Suzanna L Arcand, Karen Gambaro, Jason Madore, Ashley H Birch, Manon de Ladurantaye, Kurosh Rahimi, Diane M Provencher, Anne-Marie Mes-Masson, Celia M T Greenwood, Patricia N Tonin
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/9467faaf430c4f4db00a32587a331be2
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https://doaj.org/article/9467faaf430c4f4db00a32587a331be2

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