The genomic landscape of TP53 and p53 annotated high grade ovarian serous carcinomas from a defined founder population associated with patient outcome.
High-grade ovarian serous carcinomas (HGSC) are characterized by TP53 mutations and non-random patterns of chromosomal anomalies, where the nature of the TP53 mutation may correlate with clinical outcome. However, the frequency of common somatic genomic events occurring in HGSCs from demographically...
Guardado en:
Autores principales: | Paulina M Wojnarowicz, Kathleen Klein Oros, Michael C J Quinn, Suzanna L Arcand, Karen Gambaro, Jason Madore, Ashley H Birch, Manon de Ladurantaye, Kurosh Rahimi, Diane M Provencher, Anne-Marie Mes-Masson, Celia M T Greenwood, Patricia N Tonin |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9467faaf430c4f4db00a32587a331be2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines.
por: Elisabeth Silden, et al.
Publicado: (2013) -
TP53 in Myelodysplastic Syndromes
por: Yan Jiang, et al.
Publicado: (2021) -
<i>TP53</i> Combined Phenotype Score Is Associated with the Clinical Outcome of <i>TP53</i>-Mutated Myelodysplastic Syndromes
por: Mariko Yabe, et al.
Publicado: (2021) -
Comprehensive Identification of Deleterious <i>TP53</i> Missense VUS Variants Based on Their Impact on TP53 Structural Stability
por: Benjamin Tam, et al.
Publicado: (2021) -
DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.
por: Ana Sancho, et al.
Publicado: (2012)