A Novel Environmental Azole Resistance Mutation in <italic toggle="yes">Aspergillus fumigatus</italic> and a Possible Role of Sexual Reproduction in Its Emergence

A Novel Environmental Azole Resistance Mutation in <italic toggle="yes">Aspergillus fumigatus</italic> and a Possible Role of Sexual Reproduction in Its Emergence

ABSTRACT This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed. After heat shock, to which sexual but not asexual spores are highly resistant, the azole-free compost yielded 98% (49...

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Autores principales: Jianhua Zhang, Eveline Snelders, Bas J. Zwaan, Sijmen E. Schoustra, Jacques F. Meis, Karin van Dijk, Ferry Hagen, Martha T. van der Beek, Greetje A. Kampinga, Jan Zoll, Willem J. G. Melchers, Paul E. Verweij, Alfons J. M. Debets
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
Aspergillus fumigatus
ascospores
azole resistance
compost heap
conidiospores
hot spot for resistance development
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/946ea22cd3ba44e9814688dad8dc166a
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https://doaj.org/article/946ea22cd3ba44e9814688dad8dc166a

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