RSPO4-CRISPR alleviates liver injury and restores gut microbiota in a rat model of liver fibrosis
Yu et al. demonstrates the role of RSPO4, a Wnt signaling agonist, in liver fibrogenesis and its impact on the gut microbiome. By knocking out RSPO4 gene in fibrotic-liver rat model, they show that it relieved liver fibrosis in rats and restored the microflora composition, highlighting its potential...
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| Main Authors: | , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/947c323cd3b446e695a7975e2c4376da |
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