Role of IGF-1R in ameliorating apoptosis of GNE deficient cells

Abstract Sialic acids (SAs) are nine carbon acidic amino sugars, found at the outermost termini of glycoconjugates performing various physiological and pathological functions. SA synthesis is regulated by UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) that catalyzes rate limiting steps. Mutations in GNE...

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Autores principales: Reema Singh, Priyanka Chaudhary, Ranjana Arya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/94c0bda6a2d24ae18cada520f4ecab2f
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