Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction

Abstract T-cell activation and cellular expansion by common gamma chain cytokines such as Interleukin-2 is necessary for adaptive immunity. However, when unregulated these same pathways promote pathologies ranging from autoimmune disorders to cancer. While the functional role of Interleukin-2 and do...

Full description

Saved in:
Bibliographic Details
Main Authors: Armando Estrada, Alejandro C. Rodriguez, Georgialina Rodriguez, Alice H. Grant, Yoshira M. Ayala-Marin, Amy J. Arrieta, Robert A. Kirken
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/9512cc6ef415433aa641845f6ef594ca
Tags: Add Tag
No Tags, Be the first to tag this record!