Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction
Abstract T-cell activation and cellular expansion by common gamma chain cytokines such as Interleukin-2 is necessary for adaptive immunity. However, when unregulated these same pathways promote pathologies ranging from autoimmune disorders to cancer. While the functional role of Interleukin-2 and do...
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Main Authors: | , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/9512cc6ef415433aa641845f6ef594ca |
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