Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction

Abstract T-cell activation and cellular expansion by common gamma chain cytokines such as Interleukin-2 is necessary for adaptive immunity. However, when unregulated these same pathways promote pathologies ranging from autoimmune disorders to cancer. While the functional role of Interleukin-2 and do...

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Autores principales: Armando Estrada, Alejandro C. Rodriguez, Georgialina Rodriguez, Alice H. Grant, Yoshira M. Ayala-Marin, Amy J. Arrieta, Robert A. Kirken
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9512cc6ef415433aa641845f6ef594ca
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