TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss.

Trpm8 (transient receptor potential cation channel, subfamily M, member 8) is expressed by sensory neurons and is involved in the detection of environmental cold temperatures. TRPM8 activity triggers an increase in uncoupling protein 1 (Ucp1)-dependent brown adipose tissue (BAT) thermogenesis. Bone...

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Autores principales: Adriana Lelis Carvalho, Annika Treyball, Daniel J Brooks, Samantha Costa, Ryan J Neilson, Michaela R Reagan, Mary L Bouxsein, Katherine J Motyl
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/953e1edcb71d47958ff718fb0188a599
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