Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from the venom of Crotalus durissus terrificus

Abstract Chikungunya virus (CHIKV) is the etiologic agent of Chikungunya fever, a globally spreading mosquito-borne disease. There is no approved antiviral or vaccine against CHIKV, highlighting an urgent need for novel therapies. In this context, snake venom proteins have demonstrated antiviral act...

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Autores principales: Igor Andrade Santos, Jacqueline Farinha Shimizu, Débora Moraes de Oliveira, Daniel Oliveira Silva Martins, Léia Cardoso-Sousa, Adélia Cristina Oliveira Cintra, Victor Hugo Aquino, Suely Vilela Sampaio, Nilson Nicolau-Junior, Robinson Sabino-Silva, Andres Merits, Mark Harris, Ana Carolina Gomes Jardim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/95497c7a0e3b4bd78a66109113693206
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