Olfactory dysfunction and its measurement in the clinic

The sense of smell is largely taken for granted by laypersons and medical professionals alike. Indeed, its role in determining the flavor of foods and beverages, as well as in warning of, or protecting against, environmental hazards, often goes unrecognized. This is exemplified, in part, by the fact...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Richard L. Doty
Formato: article
Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2015
Materias:
Acceso en línea:https://doaj.org/article/956ad5b8fde3449496297cf2f172d072
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:956ad5b8fde3449496297cf2f172d072
record_format dspace
spelling oai:doaj.org-article:956ad5b8fde3449496297cf2f172d0722021-12-02T13:40:05ZOlfactory dysfunction and its measurement in the clinic2095-881110.1016/j.wjorl.2015.09.007https://doaj.org/article/956ad5b8fde3449496297cf2f172d0722015-09-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881115300202https://doaj.org/toc/2095-8811The sense of smell is largely taken for granted by laypersons and medical professionals alike. Indeed, its role in determining the flavor of foods and beverages, as well as in warning of, or protecting against, environmental hazards, often goes unrecognized. This is exemplified, in part, by the fact that most patients presenting to medical clinics with âtasteâ problems are typically subjected to complex brain imaging and gastroenterological tests without the sense of smell even being tested or considered as a basis of the problem. Aside from frank deficiencies in sweet, sour, bitter, salty and savory (umami) sensations, âtasteâ disorders most commonly reflect inadequate stimulation of the olfactory receptors via the retronasal route; i.e., from volatiles passing to the receptors from the oral cavity through the nasal pharynx. This article describes the two most common procedures for measuring the sense of smell in the clinic and provides examples of the application of these tests to diseases and other disorders frequently associated with smell loss. Basic issues related to olfactory testing and evaluation are addressed. It is pointed out that smell loss, particularly in later life, can be a harbinger for not only a range of neurodegenerative diseases, but can be a prognostic indicator of early mortality. Keywords: Allergy, Polyposis, Nasal disease, Rhinosinusitis, Smell, Psychophysics, Olfaction, IatrogenesisRichard L. DotyKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 1, Iss 1, Pp 28-33 (2015)
institution DOAJ
collection DOAJ
language EN
topic Otorhinolaryngology
RF1-547
Surgery
RD1-811
spellingShingle Otorhinolaryngology
RF1-547
Surgery
RD1-811
Richard L. Doty
Olfactory dysfunction and its measurement in the clinic
description The sense of smell is largely taken for granted by laypersons and medical professionals alike. Indeed, its role in determining the flavor of foods and beverages, as well as in warning of, or protecting against, environmental hazards, often goes unrecognized. This is exemplified, in part, by the fact that most patients presenting to medical clinics with âtasteâ problems are typically subjected to complex brain imaging and gastroenterological tests without the sense of smell even being tested or considered as a basis of the problem. Aside from frank deficiencies in sweet, sour, bitter, salty and savory (umami) sensations, âtasteâ disorders most commonly reflect inadequate stimulation of the olfactory receptors via the retronasal route; i.e., from volatiles passing to the receptors from the oral cavity through the nasal pharynx. This article describes the two most common procedures for measuring the sense of smell in the clinic and provides examples of the application of these tests to diseases and other disorders frequently associated with smell loss. Basic issues related to olfactory testing and evaluation are addressed. It is pointed out that smell loss, particularly in later life, can be a harbinger for not only a range of neurodegenerative diseases, but can be a prognostic indicator of early mortality. Keywords: Allergy, Polyposis, Nasal disease, Rhinosinusitis, Smell, Psychophysics, Olfaction, Iatrogenesis
format article
author Richard L. Doty
author_facet Richard L. Doty
author_sort Richard L. Doty
title Olfactory dysfunction and its measurement in the clinic
title_short Olfactory dysfunction and its measurement in the clinic
title_full Olfactory dysfunction and its measurement in the clinic
title_fullStr Olfactory dysfunction and its measurement in the clinic
title_full_unstemmed Olfactory dysfunction and its measurement in the clinic
title_sort olfactory dysfunction and its measurement in the clinic
publisher KeAi Communications Co., Ltd.
publishDate 2015
url https://doaj.org/article/956ad5b8fde3449496297cf2f172d072
work_keys_str_mv AT richardldoty olfactorydysfunctionanditsmeasurementintheclinic
_version_ 1718392632832425984