The mutREAD method detects mutational signatures from low quantities of cancer DNA

Sequencing tumour genomes can reveal information about the processes that drive the formation of cancer. Here, the authors describe a method that can detect these mutational signatures from small amounts of DNA and degraded samples.

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Autores principales:	Juliane Perner, Sujath Abbas, Karol Nowicki-Osuch, Ginny Devonshire, Matthew D. Eldridge, Simon Tavaré, Rebecca C. Fitzgerald
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/956e89249c06462089e01b56f371ccef
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spelling	oai:doaj.org-article:956e89249c06462089e01b56f371ccef2021-12-02T17:14:22ZThe mutREAD method detects mutational signatures from low quantities of cancer DNA10.1038/s41467-020-16974-32041-1723https://doaj.org/article/956e89249c06462089e01b56f371ccef2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16974-3https://doaj.org/toc/2041-1723Sequencing tumour genomes can reveal information about the processes that drive the formation of cancer. Here, the authors describe a method that can detect these mutational signatures from small amounts of DNA and degraded samples.Juliane PernerSujath AbbasKarol Nowicki-OsuchGinny DevonshireMatthew D. EldridgeSimon TavaréRebecca C. FitzgeraldNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Juliane Perner Sujath Abbas Karol Nowicki-Osuch Ginny Devonshire Matthew D. Eldridge Simon Tavaré Rebecca C. Fitzgerald The mutREAD method detects mutational signatures from low quantities of cancer DNA
description	Sequencing tumour genomes can reveal information about the processes that drive the formation of cancer. Here, the authors describe a method that can detect these mutational signatures from small amounts of DNA and degraded samples.
format	article
author	Juliane Perner Sujath Abbas Karol Nowicki-Osuch Ginny Devonshire Matthew D. Eldridge Simon Tavaré Rebecca C. Fitzgerald
author_facet	Juliane Perner Sujath Abbas Karol Nowicki-Osuch Ginny Devonshire Matthew D. Eldridge Simon Tavaré Rebecca C. Fitzgerald
author_sort	Juliane Perner
title	The mutREAD method detects mutational signatures from low quantities of cancer DNA
title_short	The mutREAD method detects mutational signatures from low quantities of cancer DNA
title_full	The mutREAD method detects mutational signatures from low quantities of cancer DNA
title_fullStr	The mutREAD method detects mutational signatures from low quantities of cancer DNA
title_full_unstemmed	The mutREAD method detects mutational signatures from low quantities of cancer DNA
title_sort	mutread method detects mutational signatures from low quantities of cancer dna
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/956e89249c06462089e01b56f371ccef
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The mutREAD method detects mutational signatures from low quantities of cancer DNA

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