PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia

Abstract Insulin-like growth factor-I (IGF-I) is involved in the maturation and maintenance of neurons, and impaired IGF-I signaling has been shown to play a role in various neurological diseases including stroke. The aim of the present study was to investigate the efficacy of an optimized IGF-I var...

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Autores principales: Kim Parker, Antonio Berretta, Stefanie Saenger, Manaswini Sivaramakrishnan, Simon A. Shirley, Friedrich Metzger, Andrew N. Clarkson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9573be34d1cf477683505c56800f4a1c
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